Related Experiment Video
Updated: Jul 26, 2025

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
Published on: July 20, 2022
Granuloma formation after repeated episodes of peritoneal dialysis catheter-related infection, a case report
Fang Cao1, Li Zhang1, Yiping Ruan1
1Department of Nephrology, Provincial Clinical College, Fujian Medical University, Fujian Provincial Hospital, 350001, Fuzhou, China.
Background:
Peritoneal catheter related infection is one of the main complications and the major cause of technical failure of peritoneal dialysis (PD) treatment. However, PD catheter tunnel infection can be difficult to diagnosis and resolve. We presented a rare case in which a granuloma formation after repeated episodes of peritoneal dialysis catheter-related infection.
Case Presentation:
A 53-year-old female patient with kidney failure due to chronic glomerulonephritis treated with peritoneal dialysis for 7 years. The patient had repeated exit-site and tunnel inflammation, and repeated suboptimal courses of antibiotics. She switched to hemodialysis after 6 years in a local hospital without the peritoneal dialysis catheter being removed. The patient complained of an abdominal wall mass that lasted for several months. She was admitted to the Department of surgery to undergo mass resection. The resected tissue of the abdominal wall mass was sent for pathological examination. The result showed foreign body granuloma with necrosis and abscess formation. After the surgery, the infection did not recur.
Conclusions:
The following key points can be learned from this case: 1. It is important to strengthen patient follow-up. 2.The PD catheter should be removed as early as possible in patients who do not need long-term PD, especially in patients with a history of exit-site and tunnel infections. 3. For patients presenting abnormal subcutaneous mass, attention should be paid to the possibility of the granuloma formation of infected Dacron cuffs of the PD catheter. If catheter infection occurs repeatedly, catheter removal and debridement should be considered.
Insights
Peritoneal catheter infections can lead to granuloma formation, a rare complication of peritoneal dialysis (PD). Early catheter removal is crucial for patients with recurrent infections to prevent such issues.
Area of Science:
- Nephrology
- Infectious Diseases
- Surgical Pathology
Background:
- Peritoneal dialysis (PD) is a life-sustaining treatment for kidney failure.
- PD catheter-related infections, particularly tunnel infections, are challenging to diagnose and treat.
- These infections are a primary cause of PD treatment failure.
Observation:
- A 53-year-old female PD patient experienced recurrent exit-site and tunnel infections over 7 years.
- Despite switching to hemodialysis, the patient developed an abdominal wall mass due to a retained PD catheter.
- Pathological examination revealed foreign body granuloma with necrosis and abscess formation.
Findings:
- Repeated PD catheter-related infections can result in foreign body granuloma formation.
- Granuloma formation may present as an abdominal wall mass, mimicking other conditions.
- Prompt diagnosis and management, including catheter removal and debridement, are essential.
Implications:
- Strengthening patient follow-up is critical for early detection of PD complications.
- Early removal of PD catheters in non-long-term PD patients, especially those with infection history, is recommended.
- Suspect granuloma formation in patients with a history of PD catheter infections presenting with subcutaneous masses.
Related Concept Videos
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Peritoneal Dialysis I: Introduction and Procedure
Urinary Tract Infection II: Pathophysiology
Peritoneal Dialysis III: Nursing Management
Acute Pyelonephritis I: Introduction
Renal Corpuscle
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...

