Granuloma formation after repeated episodes of peritoneal dialysis catheter-related infection, a case report

Fang Cao1, Li Zhang1, Yiping Ruan1

  • 1Department of Nephrology, Provincial Clinical College, Fujian Medical University, Fujian Provincial Hospital, 350001, Fuzhou, China.

BMC Nephrology
|June 15, 2023
PubMed
Abstract

Insights

Peritoneal catheter infections can lead to granuloma formation, a rare complication of peritoneal dialysis (PD). Early catheter removal is crucial for patients with recurrent infections to prevent such issues.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Surgical Pathology

Background:

  • Peritoneal dialysis (PD) is a life-sustaining treatment for kidney failure.
  • PD catheter-related infections, particularly tunnel infections, are challenging to diagnose and treat.
  • These infections are a primary cause of PD treatment failure.

Observation:

  • A 53-year-old female PD patient experienced recurrent exit-site and tunnel infections over 7 years.
  • Despite switching to hemodialysis, the patient developed an abdominal wall mass due to a retained PD catheter.
  • Pathological examination revealed foreign body granuloma with necrosis and abscess formation.

Findings:

  • Repeated PD catheter-related infections can result in foreign body granuloma formation.
  • Granuloma formation may present as an abdominal wall mass, mimicking other conditions.
  • Prompt diagnosis and management, including catheter removal and debridement, are essential.

Implications:

  • Strengthening patient follow-up is critical for early detection of PD complications.
  • Early removal of PD catheters in non-long-term PD patients, especially those with infection history, is recommended.
  • Suspect granuloma formation in patients with a history of PD catheter infections presenting with subcutaneous masses.

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