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Evolution of bioprinting and current applications.

Laura Mendoza-Cerezo1, M Rodríguez-Rego Jesús1, Antonio Macías-García2

  • 1Departamento de Expresión Gráfica, Escuela de Ingenierías Industriales, Universidad de Extremadura, Avenida de Elvas, s/n. 06006-Badajoz, Spain.

International Journal of Bioprinting
|June 16, 2023
PubMed
Summary

Bioprinting technology shows significant medical advancements, enabling tissue regeneration and organ manufacturing. This review highlights key developments, offering hope for solving organ donor shortages and improving healthcare.

Keywords:
3D printingBioprintingOrgan cultureTissue engineeringTissue regeneration

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Area of Science:

  • Biotechnology
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Bioprinting offers vast potential across science and biotechnology.
  • Medical applications focus on printing cells and tissues for skin regeneration and organ fabrication.
  • Viable human organs like hearts, kidneys, and bones are targets for bioprinting.

Purpose of the Study:

  • To provide a chronological overview of bioprinting technique developments.
  • To analyze the current status and medical applications of bioprinting.
  • To review progress in bioprinting from 1998 to the present.

Main Methods:

  • A comprehensive literature search was conducted.
  • Databases searched included SCOPUS, Web of Science, and PubMed.
  • 122 selected articles from 31,603 initial papers were analyzed.

Main Results:

  • The review covers significant medical advances in bioprinting.
  • Key applications and current possibilities of the technique are detailed.
  • Progress demonstrates increasing proximity to total reconstruction of damaged tissues and organs.

Conclusions:

  • Bioprinting is a valuable tool with substantial application potential.
  • The technique holds promise for addressing healthcare challenges, including organ donor shortages.
  • Future expectations for bioprinting in tissue and organ reconstruction are optimistic.