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Corrigendum: Identification of extremely GC-rich micro RNAs for RT-qPCR data normalization in human plasma

Volker Baumann1, Angelos-Theodoros Athanasiou1, Omid R Faridani2,3

  • 1Genomics Core Facility, VetCore, University of Veterinary Medicine, Vienna, Austria.

Frontiers in Genetics
|June 16, 2023
PubMed

Keywords:
cognitive stress-copinghuman plasma miRNAsmiRNA expression microarraymiRNA reference genesqPCR normalizationsmall-RNA sequencingstem-loop reverse-transcription quantitative PCR

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MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA ends...
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MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...