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Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

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Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
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The Arch of Aorta01:10

The Arch of Aorta

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The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...
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Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

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Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
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Related Experiment Video

Updated: Jul 26, 2025

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
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Flow diversion for posterior circulation aneurysms: a multicenter retrospective study.

Peng Qi1, Xin Tong2, Xin Liang3

  • 1Department of Neurosurgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.

Therapeutic Advances in Neurological Disorders
|June 16, 2023
PubMed
Summary

Flow diverter treatment for posterior circulation aneurysms shows good outcomes, particularly for dissecting types. However, careful consideration is advised due to potential complications with certain methods.

Keywords:
Tubridge embolization deviceflow diversionoutcomepipeline embolization deviceposterior circulation

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Area of Science:

  • Neurosurgery
  • Endovascular Therapy
  • Cerebrovascular Diseases

Background:

  • Intracranial aneurysms affect 3% globally, with posterior circulation (PC) aneurysms posing higher treatment risks.
  • Improving survival and quality of life for PC aneurysm patients is a critical neurovascular challenge.

Purpose of the Study:

  • To evaluate the efficacy and safety of flow diverter (FD) treatment for PC aneurysms.
  • To compare outcomes based on different FD application methods and aneurysm subtypes.

Main Methods:

  • A multicenter retrospective study of 252 PC aneurysms treated with Pipeline Embolization Device (PED) or Tubridge Embolization Device (TED) from 2015-2020.
  • Analysis of primary outcomes including perioperative complications, clinical outcomes, and aneurysm occlusion rates.
  • Logistic regression models were used to identify risk factors for outcomes.

Main Results:

  • Overall, FD treatment resulted in 7.5% major perioperative complications, 91.0% favorable clinical outcomes, and 79.1% complete occlusion.
  • Dissecting aneurysms demonstrated superior clinical and occlusion outcomes.
  • Basilar artery location was independently associated with outcomes; aneurysm size was not.
  • Tubridge Embolization Device (TED) showed similar efficacy to Pipeline Embolization Device (PED) but higher complication rates.

Conclusions:

  • Flow diverter treatment is effective for PC aneurysms, offering good clinical and occlusion rates with acceptable complications, especially for dissecting and non-basilar artery aneurysms.
  • Adjunctive treatments like coiling, multi-stent, or tandem approaches did not improve outcomes.
  • Careful patient selection is recommended for FD treatment of PC aneurysms.