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Updated: Jul 18, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
Published on: April 4, 2025
Effects of unilateral nephrectomy during early pregnancy
Abstract:
Litter data and kidney growth parameters in Wistar rats uninephrectomized (UNX) or sham-operated (SO) on the 5th-7th day of gestation, and in unoperated controls (C) were investigated at 1 day and at 6 wk postpartum. Gestation period, litter size, sex ratio of pups, and pup weight at birth did not differ among the groups. At 6 wk, pups from UNX mothers displayed retarded growth. Compensatory kidney growth following UNX in pregnant rats was predictable for wet weight, but dry weight compensation was transient and limited.
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