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Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
Published on: September 20, 2024
[MR morphometry in epileptology: progress and perspectives]
E G Potemkina1, T A Salomatina1, E V Andreev1
1Almazov National Medical Research Centre, Polenov Neurosurgery Research Institute, St. Petersburg, Russia.
Abstract:
Morphometric MRI analysis improves neuroimaging of structural changes in epilepsy.
Objective:
To investigate diagnostic potential of MR brain morphometry in neurosurgical epileptology.
Material And Methods:
An interdisciplinary working group reviewed the studies devoted to MR morphometry in epileptology as a part of state assignment No. 056-00119-22-00. Study subject was trials of MR-morphometry in epilepsy. Searching for literature data was conducted in international and national databases between 2017 and 2022 using certain keywords. Final analysis included 36 publications.
Results:
Currently, MR brain morphometry allows measurement of cortical volume and thickness, surface area and depth of furrows, as well as analysis of cortical tortuosity and fractal changes. In neurosurgical epileptology, MR-morphometry has the greatest diagnostic value in MR-negative epilepsy. This method simplifies preoperative diagnosis and reduces costs.
Conclusion:
Morphometry in neurosurgical epileptology is an additional method for verifying the epileptogenic zone. Automated programs simplify application of this method.
