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Metabolomic Analysis of Rat Brain by High Resolution Nuclear Magnetic Resonance Spectroscopy of Tissue Extracts
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Proteome Profiling of Rat Brain Cortical Changes during Early Postnatal Brain Development.

Witold M Winnik1, William Padgett1, Emily M Pitzer1

  • 1Center for Public Health and Environmental Assessment, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, United States.

Journal of Proteome Research
|June 16, 2023
PubMed
Summary

This study used label-free quantitation (LFQ) to profile rat brain development, finding significant similarities between rat and mouse cortex proteomes. Male and female rat brain profiles showed high correlation, validating the LFQ method.

Keywords:
early postnatal brain cortex developmenthigh-resolution MSlabel-free quantitationnanoflow-LC/MS

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