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[Early changes in ventricular function in diastolic phase in the resting coronary patient]
Giornale Italiano Di Cardiologia
|May 1, 1986
Summary
Coronary artery disease patients with normal systolic function show impaired left ventricular diastolic function. This diastolic dysfunction may be an early sign of ischemic ventricle alterations.
Area of Science:
- Cardiology
- Cardiovascular Physiology
Context:
- Coronary artery disease (CAD) can affect cardiac function.
- Preserved systolic performance in CAD patients may mask underlying issues.
- Left ventricular diastolic function is crucial for cardiac health.
Purpose:
- To evaluate left ventricular diastolic function in CAD patients with preserved systolic function.
- To compare diastolic and systolic indices between CAD patients and healthy controls.
Summary:
- Systolic ventricular function was comparable between 25 CAD patients and 14 controls.
- Significant differences were observed in diastolic indices, including lower diastolic pressure and altered relaxation time in CAD patients.
- Impaired left ventricular diastolic phase is a potential early indicator of ischemic ventricle changes.
Impact:
- Highlights diastolic dysfunction as an early marker in CAD.
- Suggests diastolic assessment is important for managing CAD patients.
- Provides insights into the early functional alterations in ischemic heart disease.