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Higher versus lower blood pressure targets after cardiac arrest: A meta-analysis of randomized controlled trials

Huzaifa Ahmad Cheema1, Arman Shafiee2, Mohammad Mobin Teymouri Athar3

  • 1Department of Cardiology, King Edward Medical University, Lahore, Pakistan.

Indian Heart Journal
|June 16, 2023
PubMed

Insights

This meta-analysis found no significant difference in mortality for higher versus lower blood pressure targets in out-of-hospital cardiac arrest patients. Further large-scale trials are needed to confirm these findings on blood pressure management.

Area of Science:

  • Cardiology
  • Critical Care Medicine
  • Emergency Medicine

Background:

  • Blood pressure management is crucial for out-of-hospital cardiac arrest (OHCA) survivors.
  • Previous studies on optimal blood pressure targets have yielded inconclusive results.
  • Limited data from underpowered randomized controlled trials (RCTs) exist.

Conclusions:

  • Current evidence does not support the routine use of higher blood pressure targets in post-OHCA patients.
  • Findings suggest that current blood pressure targets do not significantly impact major outcomes.
  • Larger, well-designed RCTs with homogenous blood pressure goals are necessary for definitive conclusions.

Keywords:
Blood pressureCardiac arrestMean arterial pressureMeta-analysis

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