Related Experiment Video
Updated: Jun 25, 2026

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
Published on: July 29, 2014
Opioid-Sparing Pain Control after Rhinoplasty: Updated Review of the Literature.
Rui Han Liu1, Lucy J Xu1, Linda N Lee1
1Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Massachusetts Eye and Ear, Boston, Massachusetts.
Opioid-sparing pain management in rhinoplasty is crucial. Multimodal strategies, including acetaminophen, NSAIDs, and gabapentin, minimize opioid use while ensuring adequate pain control post-surgery.
Area of Science:
- Plastic Surgery
- Pain Management
- Pharmacology
Background:
- Rhinoplasty is a common elective surgery with significant potential for opioid overprescription.
- The opioid crisis necessitates effective pain management strategies that reduce reliance on opioids.
- Inadequate pain control post-surgery can lead to patient dissatisfaction and negative postoperative experiences.
Approach:
- Implementing perioperative interventions at preoperative, intraoperative, and postoperative stages.
- Utilizing multimodal opioid-sparing techniques: acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs), and gabapentin.
- Employing preoperative counseling, intraoperative nerve blocks, long-acting analgesia, and modified surgical techniques.
Key Points:
- Opioid overprescription is common in rhinoplasty, with patients often using less than 50% of prescribed medication.
- Excess opioids pose risks for misuse and diversion.
- Multimodal pain management optimizes postoperative outcomes and minimizes opioid requirements.
Conclusions:
- Rhinoplasty is amenable to opioid minimization through standardized perioperative interventions.
- A multimodal approach, reserving opioids for rescue analgesia, is recommended for effective pain control.
- Successful pain management balances limiting opioid overuse with preventing inadequate pain relief.
Related Concept Videos
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Opioid Receptors: Overview
Analgesia and Pain Management
Opioid Analgesics: Morphine and Other Natural Cogeners
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Epistaxis
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...

