Management of transient bone osteoporosis: a systematic review
Filippo Migliorini1,2, Gianluca Vecchio3, Christian David Weber1
1Department of Orthopaedic, Trauma, and Reconstructive Surgery, RWTH University Hospital, 52074 Aachen, Germany.
Introduction:
Transient bone osteoporosis (TBO) is characterized by persistent pain, loss of function, no history of trauma and magnetic resonance image (MRI) findings of bone marrow edema.
Source Of Data:
PubMed, Google scholar, EMABSE and Web of Science were accessed in February 2023. No time constrains were used for the search.
Areas Of Agreement:
TBO is rare and misunderstood, typically affecting women during the third trimester of pregnancy or middle-aged men, leading to functional disability for 4-8 weeks followed by self-resolution of the symptoms.
Areas Of Controversy:
Given the limited evidence in the current literature, consensus on optimal management is lacking.
Growing Points:
This systematic review investigates current management of TBO.
Areas Timely For Developing Research:
A conservative approach leads to the resolution of symptoms and MRI findings at midterm follow-up. Administration of bisphosphonates might alleviate pain and accelerate both clinical and imaging recovery.
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