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Toxoplasmosis

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...

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Updated: Jul 5, 2026

Chronic Salmonella Infected Mouse Model

Chronic Salmonella Infected Mouse Model

Published on: May 31, 2010

Systemic salmonellosis in 4 cats.

Jesse Riker¹, Doris M Miller^2,1, Uriel Blas-Machado^2,1

¹Departments of Pathology, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.

Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc

|June 17, 2023

Summary

Severe salmonellosis in cats can be fatal, presenting with gastrointestinal signs, fever, and jaundice. This study identified Salmonella enterica serovars Enteritidis and Typhimurium as causative agents in four feline cases.

Keywords:

Salmonella spp cats septicemia systemic infection

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Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice

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Published on: July 29, 2022

Area of Science:

Veterinary Medicine
Infectious Diseases
Bacteriology

Background:

Salmonellosis, a bacterial infection caused by Salmonella species, can affect various animal species, including cats.
Clinical presentations and pathological findings of salmonellosis in felines can vary, potentially leading to severe illness and mortality.
Understanding the specific serovars and their impact is crucial for diagnosis and treatment of feline salmonellosis.

Purpose of the Study:

To describe the clinical, gross, and histologic findings in four cases of feline salmonellosis.
To identify the causative Salmonella enterica serovars in affected cats.
To correlate clinical signs with pathological changes and bacterial identification.

Main Methods:

Case series analysis of four cats diagnosed with salmonellosis.
Clinical data collection including signs, outcome, and physical examination findings.
Gross necropsy and histologic examination of tissues.
Bacteriologic culture and serotyping of Salmonella enterica isolates.

Main Results:

Clinical signs included vomiting, diarrhea, fever, dystocia, icterus, and seizures.
Pathologic findings revealed necrotizing enterocolitis, hepatocellular necrosis, and lymphoid necrosis.
Salmonella enterica subsp. enterica, serovar Enteritidis and serovar Typhimurium, were identified as the causative agents.

Conclusions:

Salmonellosis in cats can manifest with severe clinical and pathological signs, often resulting in a fatal outcome.
Necrotizing enterocolitis and hepatocellular necrosis are key histologic findings.
Salmonella enterica serovars Enteritidis and Typhimurium are significant causes of severe salmonellosis in felines.