Related Experiment Video
Updated: Jul 26, 2025

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
Predicting Dental Caries in Young Children in Primary Health Care Settings
M Fontana1, G J Eckert2, B P Katz3
1University of Michigan, Ann Arbor, MI, USA.
Insights
A new 10-item tool accurately identifies young children at high risk for cavities by age 1. This screening helps target early dental care and prevention for children needing it most.
Area of Science:
- Pediatric Dentistry
- Public Health
- Epidemiology
Background:
- Early childhood caries (ECC) is a significant public health issue, necessitating effective screening tools for early intervention.
- Identifying children at high risk for caries in primary care settings is crucial for equitable access to preventive dental services.
Purpose of the Study:
- To develop and validate a brief, parent-completed caries risk assessment tool for use in primary health care settings.
- The tool aims to accurately identify 1-year-old children at increased risk for developing cavitated caries lesions by age 4.
Main Methods:
- A longitudinal, prospective cohort study followed 985 children from age 1 to 4.
- Parental questionnaires and clinical dental examinations using the International Caries Detection and Assessment Criteria (ICDAS) were administered at multiple time points.
- Statistical analysis, including multivariable logistic regression, identified significant predictors of caries experience.
Main Results:
- A 10-item caries risk tool, administered at age 1, demonstrated good predictive agreement (AUC=0.73) for cavitated caries lesions by age 4.
- Key predictors included participation in public assistance (e.g., Medicaid), non-White race, premature birth, and specific caregiver-reported behaviors like sugary snack consumption and oral hygiene practices.
Conclusions:
- A 10-item caries risk assessment tool administered at age 1 is effective for identifying children at high risk for early childhood caries.
- This tool can facilitate targeted preventive strategies and improve access to dental care for at-risk populations in primary care settings.
Abstract:
Young children need increased access to dental prevention and care. Targeting high caries risk children first helps meet this need. The objective of this study was to develop a parent-completed, easy-to-score, short, accurate caries risk tool for screening in primary health care settings to identify children at increased risk for cavities. A longitudinal, prospective, multisite, cohort study enrolled (primarily through primary health care settings) and followed 985 (out of 1,326) 1-y-old children and their primary caregivers (PCGs) until age 4. The PCG completed a 52-item self-administered questionnaire, and children were examined using the International Caries Detection and Assessment Criteria (ICDAS) at 12 ± 3 mo (baseline), 30 ± 3 mo (80% retention), and 48 ± 3 mo of age (74% retention). Cavitated caries lesion (dmfs = decayed, missing, and filled surfaces; d = ICDAS ≥3) experience at 4 y of age was assessed and tested for associations with questionnaire items using generalized estimating equation models applied to logistic regression. Multivariable analysis used backward model selection, with a limit of 10 items. At age 4, 24% of children had cavitated-level caries experience; 49% were female; 14% were Hispanic, 41% were White, 33% were Black, 2% were other, and 10% were multiracial; 58% enrolled in Medicaid; and 95% lived in urban communities. The age 4 multivariable prediction model, using age 1 responses (area under the receiver operating characteristic curve = 0.73), included the following significant (P < 0.001) variables (odds ratios): child participating in public assistance programs such as Medicaid (1.74), being non-White (1.80-1.96), born premature (1.48), not born by caesarean section (1.28), snacking on sugary snacks (3 or more/d, 2.22; 1-2/d or weekly, 1.55), PCG cleaning the pacifier with juice/soda/honey or sweet drink (2.17), PCG daily sharing/tasting food with child using same spoon/fork/glass (1.32), PCG brushing their teeth less than daily (2.72), PCG's gums bleeding daily when brushing or PCG having no teeth (1.83-2.00), and PCG having cavities/fillings/extractions in past 2 y (1.55). A 10-item caries risk tool at age 1 shows good agreement with cavitated-level caries experience by age 4.
Related Concept Videos
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
Preventive Healthcare Services
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Primary Healthcare Services
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

