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High-intensity interval training in patients with intermittent claudication.

Sean Pymer1, Amy E Harwood2, Jonathon Prosser1

  • 1Academic Vascular Surgical Unit, Hull York Medical School, Hull.

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|June 18, 2023
PubMed
Summary

High-intensity interval training (HIIT) is a feasible and well-tolerated supervised exercise program for intermittent claudication (IC). This 6-week HIIT program showed higher completion rates and improved walking distance, suggesting it

Keywords:
High-intensity interval trainingIntermittent claudicationSupervised exercise program

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Area of Science:

  • Cardiovascular Exercise Physiology
  • Peripheral Artery Disease Management
  • Clinical Exercise Rehabilitation

Background:

  • Supervised exercise programs (SEP) for intermittent claudication (IC) suffer from low patient uptake, adherence, and completion rates.
  • A shorter, more time-efficient, 6-week high-intensity interval training (HIIT) program presents a potentially more acceptable and deliverable alternative for patients with IC.

Purpose of the Study:

  • To determine the feasibility and tolerability of a 6-week supervised HIIT program for patients diagnosed with IC.
  • To assess the potential efficacy, safety, and acceptability of HIIT as an alternative SEP for IC.

Main Methods:

  • A single-arm, proof-of-concept study conducted in secondary care.
  • Recruited patients with IC referred for usual-care SEPs.
  • Supervised HIIT delivered three times per week for 6 weeks, with feasibility, tolerability, safety, and acceptability as primary outcomes.

Main Results:

  • Of 165 eligible patients, 40 were recruited, with 78% completing the 6-week HIIT program.
  • High adherence (99% session attendance) and intensity completion (84%) were observed.
  • Significant improvements in maximum walking distance (+94 m) and SF-36 physical component summary scores (+2.2) were noted, with no serious adverse events.

Conclusions:

  • HIIT demonstrated higher completion rates compared to traditional SEPs in patients with IC.
  • The 6-week HIIT program is feasible, tolerable, safe, and potentially beneficial for individuals with IC.
  • HIIT may offer a more accessible and acceptable supervised exercise option, warranting further research comparing it directly with usual-care SEPs.