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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

Published on: February 13, 2021

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Differences in clinical outcomes, health care resource utilization and costs in heart failure patients according to

Juan Carlos López-Azor1, Juan Francisco Delgado2, Jorge Vélez3

  • 1Servicio de Cardiología, Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain; Centro de Investigación en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain; Facultad de Medicina, Universidad Europea, Madrid, Spain.

Revista Espanola De Cardiologia (English Ed.)
|June 18, 2023
PubMed

Insights

Left ventricular ejection fraction (LVEF) significantly impacts heart failure (HF) patient costs and healthcare resource utilization. Patients with reduced LVEF (HFrEF) incurred higher costs, particularly those requiring hospitalization, compared to preserved LVEF (HFpEF) patients.

Area of Science:

  • Cardiology
  • Health Economics
  • Healthcare Management

Background:

  • The economic burden and resource utilization associated with different left ventricular ejection fraction (LVEF) categories in heart failure (HF) patients remain incompletely understood.
  • Understanding these disparities is crucial for optimizing healthcare resource allocation and patient management strategies.

Purpose of the Study:

  • To compare health care resource utilization (HCRU) and associated costs among patients with heart failure (HF) stratified by LVEF.
  • To investigate the impact of reduced (HFrEF), mildly reduced (HFmrEF), and preserved (HFpEF) ejection fraction on clinical outcomes and economic factors.

Main Methods:

  • A retrospective observational study analyzed data from 1287 patients with a primary HF diagnosis in Spain (2018).
  • Patients were categorized into HFrEF, HFmrEF, and HFpEF groups.
  • One-year clinical outcomes, HCRU, and costs were compared across these LVEF groups.

Main Results:

  • Patients with HFrEF exhibited higher hospitalization rates and significantly greater median annual costs (€4763 in ED group, €6321 in hospital group) compared to HFmrEF and HFpEF groups.
  • The increased costs in HFrEF patients were attributed to more frequent intensive care unit admissions and greater utilization of diagnostic and therapeutic interventions.
  • Overall median costs were €1889 for the ED group and €5008 for the hospital group, with significant differences observed across LVEF categories (P <.001).

Conclusions:

  • Left ventricular ejection fraction is a significant determinant of healthcare costs and resource utilization in heart failure patients.
  • HFrEF is associated with substantially higher healthcare expenditures, particularly for patients requiring hospitalization, underscoring the need for targeted management strategies.
Abstract

Keywords:
Análisis de costesCost analysisEjection fractionFracción de eyección del ventrículo izquierdoHealth care resourcesHeart failureHospitalizaciónHospitalizationInsuficiencia cardiacaMortalidadMortalityRecursos sanitarios

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