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Updated: Jul 26, 2025

Photogeneration of N-Heterocyclic Carbenes: Application in Photoinduced Ring-Opening Metathesis Polymerization
Published on: November 29, 2018
Photoinduced Ring-Opening and Phototoxicity of an Indolin-3-one Derivative
Susanne Doloczki1, Christoph Kern1, Karl O Holmberg2
1Department of Chemistry - BMC, Uppsala University, Box 576, 75123, Uppsala, Sweden.
Abstract:
The study of a fluorescent indolin-3-one derivative is reported that, as opposed to its previously described congeners, selectively undergoes photoactivated ring-opening in apolar solvents. The excited state involved in this photoisomerization was partially deactivated by the formation of singlet oxygen. Cell studies revealed lipid droplet accumulation and efficient light-induced cytotoxicity.
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