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Pseudotumoral Amyloidosis Presentation With Upper Digestive Bleeding.
Igor Logetto Caetité Gomes1, Alexandre de Sousa Carlos1, Angelo So Taa Kum1
1Gastroenterology, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, BRA.
Cureus
|June 19, 2023
Summary
Amyloidosis can cause upper gastrointestinal bleeding, often presenting as melena. This case highlights the importance of considering gastric amyloidosis in patients with unexplained bleeding.
Area of Science:
- Gastroenterology
- Pathology
Background:
- Amyloidosis involves extracellular deposition of abnormal fibrillar proteins.
- Gastric amyloidosis can be systemic or localized, mimicking other conditions.
- Endoscopic findings range from nodular to infiltrative lesions.
Observation:
- The patient presented with upper gastrointestinal bleeding manifesting as melena.
- Gastric amyloidosis was diagnosed as the cause of the bleeding.
- The presentation mimicked other gastrointestinal diseases.
Findings:
- Amyloidosis can present with nonspecific symptoms like nausea and weight loss.
- Gastric amyloidosis can lead to gastrointestinal bleeding, typically melena.
- Differential diagnosis is crucial due to overlapping symptoms with neoplasms and inflammatory diseases.
Implications:
- Highlights the need for high clinical suspicion for gastric amyloidosis.
- Emphasizes the diagnostic challenge posed by amyloidosis mimicking other GI pathologies.
- Underscores the importance of considering rare causes of upper GI bleeding.
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