Related Experiment Video
Updated: Jul 26, 2025

Modeling The Lifecycle Of Ebola Virus Under Biosafety Level 2 Conditions With Virus-like Particles Containing Tetracistronic Minigenomes
Published on: September 27, 2014
Generative design for COVID-19 and future pathogens using stochastic multi-agent simulation
Bokyung Lee1, Damon Lau2, Jeremy P M Mogk1
1Autodesk Research, 661 University Ave, West Tower, Ste. 200, Toronto, M5G 1MA, ON, Canada.
Abstract:
We propose a generative design workflow that integrates a stochastic multi-agent simulation with the intent of helping building designers reduce the risk posed by COVID-19 and future pathogens. Our custom simulation randomly generates activities and movements of individual occupants, tracking the amount of virus transmitted through air and surfaces from contagious to susceptible agents. The stochastic nature of the simulation requires that many repetitions be performed to achieve statistically reliable results. Accordingly, a series of initial experiments identified parameter values that balanced the trade-off between computational cost and accuracy. Applying generative design to a case study based on an existing office space reduced the predicted transmission by around 10% to 20% compared with a baseline set of layouts. Additionally, a qualitative examination of the generated layouts revealed design patterns that may reduce transmission. Stochastic multi-agent simulation is a computationally expensive yet plausible way to generate safer building designs.
More Related Videos
Related Concept Videos
Steps in Outbreak Investigation
Microorganisms in Medicine and Therapeutics
Chemical Agents for Microbial Control
Principles of Disease Surveillance
Causality in Epidemiology
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...

