Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Uterine Tubes

Uterine Tubes

The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Quantitative 3D histology reveals localized immune remodeling during early pancreatic cancer progression.

Cell press blue·2026

Same author

Distinct fibroblast and perivascular senotypes define spatial niches that regulate fibrosis.

bioRxiv : the preprint server for biology·2026

Same author

3D multi-omics tumour atlases: from technology to biology and clinical translation.

Nature reviews. Cancer·2026

Same author

Particle tracking microrheology of cancer cells in living subjects.

Materials today (Kidlington, England)·2026

Same author

Viscoelastic and Morphologic Changes in the Lumbar Intervertebral Discs of the 5xFAD Mouse Model of Alzheimer's Disease.

JOR spine·2026

Same author

Distinct senescent β-cell senotypes differentially drive islet aging and dysfunction.

bioRxiv : the preprint server for biology·2026

Same journal

A human-specific genetic modifier reconfigures large-scale cortical network dynamics underlying behavioral performance.

bioRxiv : the preprint server for biology·2026

Same journal

<i>Staphylococcus aureus</i> uses a eukaryotic-like uridyltransferase to make UDP-GlcNAc for cell wall synthesis.

bioRxiv : the preprint server for biology·2026

Same journal

Dynamic redistribution of eIF4F controls cap-dependent translation initiation.

bioRxiv : the preprint server for biology·2026

Same journal

When does additional information improve accuracy of RNA secondary structure prediction?

bioRxiv : the preprint server for biology·2026

Same journal

Normative brain-state trajectories reveal deviation from healthy aging in Alzheimer's disease.

bioRxiv : the preprint server for biology·2026

Same journal

Noradrenergic infraslow rhythm during sleep is the critical link between heart-rate dynamics and memory consolidation.

bioRxiv : the preprint server for biology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 26, 2025

An Efficient Method for Extracting Human Fallopian Tube Epithelia for Single-cell Analyses

An Efficient Method for Extracting Human Fallopian Tube Epithelia for Single-cell Analyses

Published on: March 28, 2025

Precision-engineered biomimetics: the human fallopian tube.

Ashleigh J Crawford, André Forjaz, Isha Bhorkar

Biorxiv : the Preprint Server for Biology

|June 19, 2023

Summary

This summary is machine-generated.

Researchers created a new organoid model of the human fallopian tube, offering a biologically relevant tool for studying diseases like ovarian cancer and improving reproductive health research.

More Related Videos

A Human Fallopian Tube Model for Investigation of C. trachomatis Infections

A Human Fallopian Tube Model for Investigation of C. trachomatis Infections

Published on: August 11, 2012

Somatic Genome-Engineered Mouse Models Using In Vivo Microinjection and Electroporation

Somatic Genome-Engineered Mouse Models Using In Vivo Microinjection and Electroporation

Published on: May 5, 2023

Related Experiment Videos

Last Updated: Jul 26, 2025

An Efficient Method for Extracting Human Fallopian Tube Epithelia for Single-cell Analyses

An Efficient Method for Extracting Human Fallopian Tube Epithelia for Single-cell Analyses

Published on: March 28, 2025

A Human Fallopian Tube Model for Investigation of C. trachomatis Infections

A Human Fallopian Tube Model for Investigation of C. trachomatis Infections

Published on: August 11, 2012

Somatic Genome-Engineered Mouse Models Using In Vivo Microinjection and Electroporation

Somatic Genome-Engineered Mouse Models Using In Vivo Microinjection and Electroporation

Published on: May 5, 2023

Area of Science:

Reproductive biology
Organoid technology
Cancer research

Background:

The fallopian tube is crucial for reproduction and disease, but lacks accurate models for study.
Existing organoid models offer limited insights into fallopian tube pathophysiology.
Understanding fallopian tube function is vital for fertility and ovarian cancer research.

Approach:

Developed a novel multi-compartment organoid model of the human fallopian tube.
Engineered the organoid to precisely mimic native tissue compartmentalization and cellular heterogeneity.
Utilized a 3D, single-cell resolution reference map for iterative validation.

Key Points:

The organoid model accurately reflects human fallopian tube microanatomy.
Validated molecular expression patterns and cilia-driven transport function.
Achieved high structural accuracy through iterative comparison with a reference map.

Conclusions:

This tissue-validated organoid model provides a biologically relevant platform for fallopian tube research.
Enables detailed study of physiological and pathological processes, including ovarian cancer.
Advances the development of accurate in vitro models for reproductive system research.