Exploring disease interrelationships in older inpatients: a single-centre, retrospective study

Area of Science:

• Gerontology
• Public Health
• Epidemiology

Background:

• Comorbidity significantly burdens older populations globally.
• Evidence on comorbidity patterns in southwestern China's elderly is limited.
• This study addresses the need for regional data on geriatric comorbidity.

Purpose of the Study:

• To investigate current comorbidity characteristics in individuals over 60 years old.
• To analyze correlations among co-occurring diseases in the elderly population.
• To provide data for improving clinical practice and public health policies.

Main Methods:

• Retrospective analysis of 2,995 inpatient records (2018-2022).
• Calculation of age-adjusted Charlson Comorbidity Index (ACCI).
• Disease categorization using ICD and CHIRLS, with visualization via web graphs and Apriori algorithm.

Main Results:

• High ACCI observed, increasing with age, particularly in those ≥90 years.
• Most frequent comorbidities: liver diseases, digestive diseases, and hypertension.
• Significant correlations found between digestive diseases and hypertension.

Conclusions:

• Findings offer insights into geriatric comorbidity in southwestern China.
• Results can guide future research and inform public health strategies.
• Data is valuable for medical consortiums and clinical practice adjustments.