Aortoiliac: Covered, Uncovered, CERAB as It Relates to Peripheral Arterial Disease
Sayeh Bozorghadad1, Matthew J Scheidt1, Parag J Patel1
1Department of Radiology, Vascular and Interventional Radiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Insights
Peripheral arterial disease (PAD) management is shifting. Endovascular techniques offer improved outcomes and reduced mortality compared to open surgery for aortoiliac disease.
Area of Science:
- Vascular Surgery
- Endovascular Interventions
- Cardiovascular Medicine
Background:
- Peripheral arterial disease (PAD) impacts over 200 million globally, posing significant mortality and amputation risks.
- Historically, open surgery was the gold standard for aortoiliac disease, despite high perioperative mortality.
- Advancements in endovascular technology are reshaping treatment paradigms for PAD.
Purpose of the Study:
- To compare the efficacy of open surgery versus endovascular techniques for aortoiliac disease.
- To highlight the benefits of adopting an endovascular-first approach in PAD management.
- To review novel endovascular techniques like covered endovascular reconstruction of the aortic bifurcation.
Main Methods:
- Comparative review of open surgical and endovascular treatment strategies for aortoiliac disease.
- Analysis of technical success, primary, and secondary patency rates.
- Evaluation based on TASC-II guidelines and current clinical evidence.
Main Results:
- Endovascular techniques demonstrate increasing efficacy and wider adoption for aortoiliac disease.
- Covered endovascular reconstruction shows excellent technical success and improved patency rates.
- Endovascular approaches offer a potentially lower perioperative mortality risk compared to open surgery.
Conclusions:
- A shift towards an endovascular-first approach for aortoiliac disease is supported by recent technological advancements and clinical outcomes.
- Endovascular interventions provide a viable and effective alternative to open surgery, regardless of lesion complexity.
- This approach aims to improve patient outcomes and reduce amputation rates in PAD management.
Abstract:
Peripheral arterial disease (PAD) affects over 200 million worldwide and is the leading cause of major limb amputation, with individuals suffering from PAD being at three times greater risk of dying compared with matched controls. TASC-II guidelines provide a consensus on the management of PAD based on the collaboration between international vascular specialties. These guidelines previously outlined open surgery as the gold standard for treatment of aortoiliac disease and PAD as it has demonstrated consistent long-term results. However, this approach is also associated with high perioperative mortality, especially when compared with endovascular techniques. With recent developments in endovascular technology, user technique, and experience, this approach has become more widely used as primary intervention for aortoiliac disease. One of these novel techniques includes covered endovascular reconstruction of the aortic bifurcation, which has demonstrated excellent technical success and improved primary and secondary patency rates with follow-up. The aim of this review is to compare the efficacy of these approaches to the treatment of aortoiliac disease and demonstrate the benefits of the shift toward an endovascular-first approach to treatment of this disease, regardless of lesion complexity or severity.
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