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Growth trajectories in children with cleft lip and/or palate

Rocío Gallego Sobrino1, Iris Iglesia-Altaba2, Ignacio Moral3

  • 1Instituto de Investigación Sanitaria de Aragón (IIS Aragón).

Nutricion Hospitalaria
|June 19, 2023
PubMed

Insights

Children with cleft lip and/or palate (CL/P) face nutritional challenges early in life, with growth trajectories recovering by one year but a higher rate of thinness persisting.

Area of Science:

  • Pediatric Nutrition
  • Craniofacial Anomalies
  • Growth and Development

Background:

  • Children with cleft lip and/or palate (CL/P) often experience feeding difficulties impacting nutritional status and growth.
  • Anatomical variations and surgical interventions in CL/P can further complicate early childhood development.

Purpose of the Study:

  • To analyze the growth trajectories of children with CL/P.
  • To compare the growth of CL/P patients with a healthy control cohort from Aragon, Spain.

Main Methods:

  • Retrospective longitudinal study design.
  • Recorded cleft type, surgical details, and anthropometric data (weight, length/height, BMI) from 0-6 years.
  • Calculated normalized age- and sex-specific Z-scores using WHO charts for 41 CL/P patients.

Main Results:

  • Worst nutritional status observed at three months, with significant weight and BMI deficits compared to controls.
  • Mean weight and BMI Z-scores were significantly lower at 1, 3, and 6 months.
  • Growth parameters showed recovery from six months onwards, reaching comparable levels by one year of age.

Conclusions:

  • Highest nutritional risk for CL/P patients occurs between 3-6 months.
  • Nutritional status and growth trajectories generally recover by one year compared to controls.
  • A higher prevalence of thinness persists in CL/P patients throughout childhood.
Abstract

Keywords:
Fisura labial. Fisura palatina. Crecimiento. Nutrición.

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