Related Experiment Video
Updated: Jul 26, 2025
04:52
Following the Dynamics of Structural Variants in Experimentally Evolved Populations
Published on: February 3, 2023
1.0K
Using ChromEvol to Determine the Mode of Chromosomal Evolution
Marcial Escudero1, Enrique Maguilla2, José Ignacio Márquez-Corro2
1Department of Plant Biology and Ecology, University of Seville, Seville, Spain.
Methods in Molecular Biology (Clifton, N.J.)
|June 19, 2023
Summary
ChromEvol software advances chromosome evolution analysis with new probabilistic models for polyploidy and trait evolution. Future developments will enable more complex evolutionary studies.
Area of Science:
- Computational Biology
- Evolutionary Biology
- Genomics
Background:
- The ChromEvol software pioneered likelihood-based approaches for modeling chromosome number evolution along phylogenies.
- Previous models in ChromEvol have been iteratively refined and expanded over time.
Purpose of the Study:
- To introduce and detail recent advancements in the ChromEvol software, including new models for polyploid chromosome evolution and the integration of binary trait evolution.
- To highlight the development of more sophisticated models like BiChrom and ChromoSSE.
Main Methods:
- Implementation of new parameters in ChromEvol v.2 to specifically model polyploid chromosome evolution.
- Development of the BiChrom model to accommodate distinct chromosome evolution models for binary trait states.
- Integration of chromosome evolution with speciation and extinction processes in the ChromoSSE model.
Main Results:
- ChromEvol v.2 now supports the analysis of polyploid chromosome evolution.
- The BiChrom model allows for the analysis of chromosome evolution in relation to binary characteristics.
- The ChromoSSE model offers a joint analysis of chromosome evolution, speciation, and extinction.
Conclusions:
- ChromEvol continues to evolve, offering increasingly sophisticated tools for studying chromosome number evolution.
- The latest models facilitate more comprehensive and integrated analyses of evolutionary processes.
- Future work will focus on developing even more complex models for evolutionary research.
Related Concept Videos
01:39Chromosomal Theory of Inheritance
55.6K
In 1866, Gregor Mendel published the results of his pea plant breeding experiments, providing evidence for predictable patterns in the inheritance of physical characteristics. The significance of his findings was not immediately recognized. In fact, the existence of genes was unknown at the time. Mendel referred to hereditary units as “factors.”
55.6K
02:40Chromosome Structure
4.9K
4.9K
02:54Evolutionary Relationships through Genome Comparisons
5.9K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.9K
02:05Gene Evolution - Fast or Slow?
7.2K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
In contrast, regions which code...
7.2K
02:11Forces Acting on Chromosomes
3.4K
During mitosis, chromosome movements occur through the interplay of multiple piconewton level forces. In prometaphase, these forces help in chromosome assembly or congression at the equatorial plane, eventually leading to their alignment at the metaphase plate. The forces acting on the chromosomes are space and time-dependent; therefore, they vary with the position of the chromosomes as the cell progresses through mitosis.
Microtubules and motor proteins exert two types of forces on...
Microtubules and motor proteins exert two types of forces on...
3.4K
02:31Synteny and Evolution
3.3K
John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
3.3K