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Pleomorphic Dermal Sarcoma With Metastasis to the Lung: A Case Report
Saba Shafi1, Mark Bechtel2, Carlo M Contreras3
1Departments of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH.
The American Journal of Dermatopathology
|June 19, 2023
Summary
A rare skin cancer, pleomorphic dermal sarcoma (PDS), can aggressively recur and metastasize. Distinguishing PDS from atypical fibroxanthoma is crucial for patient outcomes.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) represent a spectrum of malignant mesenchymal skin tumors.
- PDS is clinically similar to AFX but exhibits a more aggressive behavior, including higher rates of local recurrence and metastasis.

