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Methods and Measures for Investigating Microscale Motility
Karen Grace Bondoc-Naumovitz1, Hannah Laeverenz-Schlogelhofer1, Rebecca N Poon1
1Living Systems Institute, University of Exeter, Stocker Road, EX4 4QD, Exeter, UK.
Integrative and Comparative Biology
|June 19, 2023
Summary
Microscopic organisms use diverse motility mechanisms for survival. This review explores experimental and mathematical methods to study microscale movement across various biological scales.
Area of Science:
- Microscale biology
- Biophysics
- Cellular dynamics
Background:
- Organism survival and diversification depend on motility.
- Understanding microscale movement requires integrating biological and physical principles.
- Novel technologies enable deeper investigation of microscopic motile organisms.
Approach:
- Summarizes key mechanisms of microscale motility.
- Overviews diverse experimental, analytical, and mathematical methods.
- Examines techniques across molecular, individual, and population levels.
Key Points:
- Microscale motility encompasses various biological and physical phenomena.
- A range of methods, from molecular to population scales, are employed.
- Interdisciplinary approaches are crucial for studying microscale locomotion.
Conclusions:
- This review provides a foundation for microscale motility research.
- Identifies transferable techniques, challenges, and future research directions.
- Aims to guide researchers in quantifying microbial movement.
