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Updated: Jul 26, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
Published on: March 15, 2024
Why is FERONIA pleiotropic?
Alice Malivert1, Olivier Hamant2
1Laboratoire de Reproduction et Développement des Plantes, Université de Lyon, ENS de Lyon, UCBL, INRAE, CNRS, Lyon, France.
Abstract:
The plant cell wall has many roles: structure, hydraulics, signalling and immunity. Monitoring its status is therefore essential for plant life. Among many candidate cell wall sensors, FERONIA, a member of the Catharanthus roseus receptor-like kinase-1-like kinase (CrRLK1L) family, has received considerable attention, notably because of its numerous interactors and its implication in many biological pathways. Conversely, such an analytical dissection may blur its core function. Here we revisit the array of feronia phenotypes as an attempt to identify a unifying feature behind the plethora of biological and biochemical functions. We propose that the contribution of FERONIA in monitoring turgor-dependent cell wall tension may explain its pleiotropy.
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