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A Plaque-Like CD34-Positive Dermal Fibroma Presenting as an Acquired Papule
Alpa Kanji1, James Carton2, Caroline Hewitt1
1Dermatology, Imperial College Healthcare NHS (National Health Service) Trust, London, GBR.
Abstract:
CD34-positive dermal fibromas (PDFs) are cutaneous neoplasms that display a characteristic pattern of superficial dermal spindle cell proliferation on histopathology evaluation. They are clinically heterogenous in presentation and thought to follow a benign course. CD34-PDFs have features that overlap with dermatofibrosarcoma protuberans (DFSP), a locally aggressive low-grade superficial sarcoma. Cytogenetic studies are essential to distinguish the two. This report presents the case of a 38-year-old female with a CD34-PDF on the right antecubital fossa.
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