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Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
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Invasive Acantholytic Ocular Surface Squamous Neoplasia: A Rare Case.
Avi Sharma1, Sachin Daigavane1, Arvind Bhake2
1Ophthalmology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus
|June 20, 2023
Summary
Ocular surface squamous neoplasia (OSSN) is a rare eye cancer. This case highlights the uncommon acantholytic variant, emphasizing the need for accurate histopathological diagnosis to manage this sight-threatening malignancy.
Area of Science:
- Ophthalmology
- Oncology
- Pathology
Background:
- Ocular surface squamous neoplasia (OSSN) encompasses neoplastic lesions of the conjunctiva and cornea.
- OSSN is a rare, potentially sight-threatening malignancy with diagnostic challenges due to its similarity to benign lesions.
Observation:
- A 69-year-old male presented with a progressively growing invasive mass on the left eyeball, encroaching the visual axis.
- The clinical presentation mimicked other ocular surface conditions, necessitating detailed investigation.
Findings:
- Histopathological analysis confirmed a rare acantholytic variant of squamous cell carcinoma.
- The patient underwent extended enucleation for the invasive ocular tumor.
Implications:
- Accurate histopathological diagnosis is crucial for managing OSSN, particularly rare variants.
- Early detection and management of OSSN are vital to prevent vision loss and systemic metastasis.

