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Updated: Jul 26, 2025
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Published on: April 12, 2024
Eccrine Angiomatous Hamartoma with Atypical Localization Treated by Mohs Micrographic Surgery
Carmine D'Acunto1, Luca Riccioni, Francesca Scarpellini
1At M. Bufalini Hospital, Cesena, Italy, Carmine D'Acunto, MD, is Dermatologist, Department of Surgery and Trauma Center, O.U. Burn Center and Dermatology; Luca Riccioni, MD, and Francesca Scarpellini, MD, are Pathologists, Department of Clinical Pathology, O.U. Pathological Anatomy; Valeria Purpura, BD, is Biologist, Department of Surgery and Trauma Center, O.U. Burn Center and Dermatology; and Davide Melandri, MD, is Dermatologist and Plastic Surgeon, Department of Surgery and Trauma Center, O.U. Burn Center and Dermatology.
Abstract:
Eccrine angiomatous hamartoma (EAH) is a rare hamartoma characterized by a benign proliferation of eccrine glands and vascular structures in the dermis. These tumors rarely regress spontaneously, so surgical excision of the involved tissue is required when pain or enlargement occurs. Here, the authors report the clinical case of a patient affected by an extremely painful EAH with the atypical localization at the last phalanx of the thumb of the right hand with involvement of nail matrix and nail bed. This report aims to emphasize the application of Mohs micrographic surgery for the treatment of painful EAH in a very difficult area at potential risk of amputation while preserving the maximum anatomical integrity and function of the damaged area. These results can pave the way for the use of Mohs micrographic surgery for very carefully selected benign neoplasms when their surgical removal is required.
