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Updated: Jul 26, 2025
Measurement of Antibody Effects on Cellular Function of Isolated Cardiomyocytes
Published on: March 8, 2013
Comparative Determination of Natural Antibodies for the Assessment of the Cardiovascular System and the Level of
M A Myagkova1, Z V Bobrova1, E M Orlova1
1Institute of Physiologically Active Substances Federal Research Center for Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Moscow oblast, Chernogolovka, Russia.
Abstract:
A comparative analysis of natural antibodies to β-endorphin, angiotensin, dopamine, serotonin, parameters of the cardiovascular system and anxiety levels was carried out for 241 athletes of various qualifications and sports. The obtained indicators of the cardiovascular system were compared with reference values. A significant increase in the level of natural antibodies to angiotensin was established for all groups of athletes. In the case of dopamine, serotonin, these differences are associated with the qualification of the athlete, for β-endorphin, differences in the level of the indicator depending on the sport were found. A group of individuals with high levels of situational and personal anxiety was found among highly qualified athletes. An increase in blood pressure in athletes of cyclic sports and martial arts is adaptive, and in athletes of speed-strength sports it leads to a change in the walls of the myocardium. As a result of the study, the possibility of a comprehensive determination of natural antibodies and functional indicators as diagnostic markers for assessing the state of the human cardiovascular system has been shown.
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