Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Socioemotional Experience and Gender Development

Socioemotional Experience and Gender Development

Social-emotional experiences and cultural influences play significant roles in shaping gender development. During middle childhood, from ages 6 to 11, peer groups become dominant in reinforcing gender norms. Children in this age group often align with same-gender peer groups, which actively encourage behaviors that conform to traditional gender roles. For instance, boys may be discouraged from engaging in activities perceived as feminine, reinforcing culturally dictated norms about masculinity...

Socioemotional Development during Infancy

Socioemotional Development during Infancy

Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types

Cognitive Development During Adolescence

Cognitive Development During Adolescence

During adolescence, individuals experience significant cognitive development that enhances their understanding of others' emotions and thoughts, known as cognitive empathy. This period is marked by an increased ability to adapt to others' perspectives and a more nuanced understanding of others' mental states, a skill that is foundational for social problem-solving and conflict avoidance. The development of cognitive empathy relies heavily on the theory of mind — the...

Physiology of Emotion

Physiology of Emotion

The physiology of emotions is a multifaceted process involving the autonomic nervous system, brain structures, hormones, and neurotransmitters. This intricate interplay dictates how emotions manifest in the body and influence behavior.
Autonomic Nervous System
The autonomic nervous system (ANS) plays a critical role in emotional responses by regulating involuntary physiological functions. It consists of two main components: the sympathetic and parasympathetic systems. The sympathetic system...

Testosterone: Functions and Regulation

Testosterone: Functions and Regulation

The intricate hormonal interplay essential for male reproductive health begins with the release of gonadotropin-releasing hormone (GnRH) by the hypothalamus. This hormone prompts the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). LH targets the Leydig cells in the testes, stimulating them to produce and release testosterone. In concert with testosterone, FSH acts on the Sertoli cells within the seminiferous tubules to facilitate the release of...

Facial Feedback Hypothesis

Facial Feedback Hypothesis

Charles Darwin proposed that facial expressions are an evolutionary adaptation for communication. He argued that these expressions are not influenced by culture but are universal across species. For example, a snarling expression with exposed teeth signals a threat in many animals, including humans. Darwin also suggested that displaying an emotion can intensify the feeling. Smiling, for example, could enhance one's sense of happiness. This idea laid the foundation for understanding the role...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Inter-subject correlations and their behavioral associations vary across movies: Implications for generalizability.

bioRxiv : the preprint server for biology·2026

Same author

Stimulation of the human periaqueductal gray induces threat bradycardia: a case report.

Neurocase·2026

Same author

The human amygdala in threat learning and extinction.

Science advances·2026

Same author

How Temporal Predictability of Threat and Action Preparation Affect Defensive Freezing Responses.

Psychophysiology·2026

Same author

Predictors of popularity among students with intellectual disabilities: The role of prosocial and antisocial behaviours.

Journal of intellectual & developmental disability·2025

Same author

Lateral frontopolar theta-band activity supports flexible switching between emotion regulation strategies.

Scientific reports·2025

Same journal

Deaf Children's Use of Mutual Exclusivity and Eye Gaze to Determine Word Meanings in American Sign Language.

Developmental science·2026

Same journal

Adolescents and Adults Use Different Facial Movements and Vocal Cues to Express Emotions.

Developmental science·2026

Same journal

Decoding Preschool Social Dynamics: Automated Tracking of Spatial and Temporal Patterns to Investigate Social Interactions and Relationships in Peer Groups.

Developmental science·2026

Same journal

Early Life Stress Affects Human Decision Making by Increasing Expectations of Volatility.

Developmental science·2026

Same journal

The Impact of Intergroup Collaboration on In-Group Bias Between Rohingya Refugee and Bangladeshi Host Community Children.

Developmental science·2026

Same journal

Toddlers' Active Gaze Behavior Supports Self-Supervised Object Learning.

Developmental science·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 26, 2025

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Published on: March 2, 2011

Developmental shift in testosterone influence on prefrontal emotion control.

Anna Tyborowska^1,2,3, Inge Volman^4,5, Hannah C M Niermann^1,2

¹Behavioural Science Institute, Radboud University, Nijmegen, Netherlands.

Developmental Science

|June 21, 2023

Summary

This summary is machine-generated.

Testosterone

Keywords:

adulthood approach-avoidance frontal pole puberty social emotional control testosterone

More Related Videos

Psychophysiological Assessment of the Effectiveness of Emotion Regulation Strategies in Childhood

Psychophysiological Assessment of the Effectiveness of Emotion Regulation Strategies in Childhood

Published on: February 11, 2017

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Published on: December 2, 2015

Related Experiment Videos

Last Updated: Jul 26, 2025

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Published on: March 2, 2011

Psychophysiological Assessment of the Effectiveness of Emotion Regulation Strategies in Childhood

Psychophysiological Assessment of the Effectiveness of Emotion Regulation Strategies in Childhood

Published on: February 11, 2017

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Published on: December 2, 2015

Area of Science:

Neuroendocrinology
Developmental Neuroscience
Social Neuroscience

Background:

Testosterone's role in social-emotional behavior differs between adolescents and adults.
During adolescence, testosterone is linked to anterior prefrontal cortex (aPFC) involvement in emotion control, a relationship reversed in adulthood.
Rodent studies suggest testosterone shifts from a neurodevelopmental to a social-activating role during puberty.

Purpose of the Study:

To investigate if testosterone's functional transition observed in rodents also occurs in humans.
To explore the role of testosterone in the neural control of social-emotional behavior during adolescent and young adult development.
To examine changes in testosterone's influence on the prefrontal-amygdala circuit across development.

Main Methods:

Prospective longitudinal study with 71 participants tested at ages 14, 17, and 20 years.
Utilized a functional magnetic resonance imaging (fMRI)-adapted approach-avoidance (AA) task assessing responses to social-emotional stimuli.
Measured testosterone levels and their correlation with neural activity during the AA task.

Main Results:

Testosterone's effect on aPFC engagement diminished from middle to late adolescence.
By young adulthood, testosterone's role shifted to an activational one, impairing neural emotion control.
Increased testosterone-modulated amygdala reactivity was observed with this functional shift.

Conclusions:

Testosterone's neuro-endocrine function in emotion regulation undergoes a significant transition during human development.
This transition involves a shift from a neurodevelopmental role in adolescence to an activational role in young adulthood.
Findings highlight the maturation of the testosterone-dependent prefrontal-amygdala circuit governing emotion control from adolescence to young adulthood.