Iodine Anion Catalyzed Cross-Dehydrogenative Aromatization for Access to Aromatic Amines
Yan Shi1, Cui Yi1, Xiaoli Huang1
1Department of Material Chemistry, School of Chemistry, and Engineering Research Center of Energy Storage Materials and Devices of Ministry of Education, Xi'an Jiaotong University, Xi'an 710049, P. R. China.
Abstract:
A highly efficient iodine anion catalyzed cross-dehydrogenative aromatization of cyclohexenones with amines has been developed under metal-free conditions, which affords aromatic amines in good to excellent yields with a broad substrate scope. Meanwhile, this reaction provides a new method for the construction of C(sp2)-N bonds and also a new strategy for slow generation of oxidants or electrophiles via in situ dehalogenation. Moreover, this protocol affords a rapid and concise approach to chiral NOBIN derivatives.
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