Bizarre blue nevus: a case report with deoxyribonucleic acid content analysis

A case report of an unusual variant of blue nevus is presented. The lesion demonstrated striking cytologic atypia but lacked clinical and certain histologic features of malignancy. Similarities and differences between this lesion and atypical blue nevus and Spitz nevus are discussed. An analysis of the deoxyribonucleic acid levels in lesional cells was consistent with polyploidy. This supports the interpretation of the lesion as atypical but is not inconsistent with a benign diagnosis.