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Incremental hemodialysis in pediatric patients
Gurevich Evgenia1,2,3, Falush Yafa1, Alfandari Hadas1,4
1Institute of Nephrology, Schneider Children's Medical Center of Israel, 14 Kaplan St, 4920235, Petach Tikva, Israel.
Journal of Nephrology
|June 21, 2023
Summary
Incremental hemodialysis is a viable option for pediatric patients, potentially improving quality of life. This approach may reduce dialysis burden without negatively impacting clinical outcomes in children.
Area of Science:
- Pediatric Nephrology
- Renal Replacement Therapy
Background:
- Incremental hemodialysis adjusts dialysis dose based on residual kidney function.
- Limited data exists on incremental hemodialysis specifically in pediatric patients.
Purpose of the Study:
- To compare the characteristics and outcomes of pediatric patients initiating incremental hemodialysis versus conventional thrice-weekly hemodialysis.
Main Methods:
- Retrospective analysis of children starting hemodialysis between January 2015 and July 2020.
- Comparison of patient characteristics and outcomes between incremental and thrice-weekly hemodialysis groups.
Main Results:
- Incremental hemodialysis group had more males, congenital anomalies, higher urine output, and less left ventricular hypertrophy at baseline and follow-up.
- Fewer patients on incremental hemodialysis had left ventricular hypertrophy and low urine output at last follow-up.
- No significant differences in metabolic or growth parameters were observed between groups.
Conclusions:
- Incremental hemodialysis is a feasible option for selected pediatric patients.
- This approach may enhance quality of life and decrease dialysis burden.
- Clinical outcomes are not compromised when initiating incremental hemodialysis in children.
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