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Incremental hemodialysis in pediatric patients

Gurevich Evgenia1,2,3, Falush Yafa1, Alfandari Hadas1,4

  • 1Institute of Nephrology, Schneider Children's Medical Center of Israel, 14 Kaplan St, 4920235, Petach Tikva, Israel.

Journal of Nephrology
|June 21, 2023
PubMed

Insights

Incremental hemodialysis is a viable option for pediatric patients, potentially improving quality of life. This approach may reduce dialysis burden without negatively impacting clinical outcomes in children.

Area of Science:

  • Pediatric Nephrology
  • Renal Replacement Therapy

Background:

  • Incremental hemodialysis adjusts dialysis dose based on residual kidney function.
  • Limited data exists on incremental hemodialysis specifically in pediatric patients.

Purpose of the Study:

  • To compare the characteristics and outcomes of pediatric patients initiating incremental hemodialysis versus conventional thrice-weekly hemodialysis.

Main Methods:

  • Retrospective analysis of children starting hemodialysis between January 2015 and July 2020.
  • Comparison of patient characteristics and outcomes between incremental and thrice-weekly hemodialysis groups.

Main Results:

  • Incremental hemodialysis group had more males, congenital anomalies, higher urine output, and less left ventricular hypertrophy at baseline and follow-up.
  • Fewer patients on incremental hemodialysis had left ventricular hypertrophy and low urine output at last follow-up.
  • No significant differences in metabolic or growth parameters were observed between groups.

Conclusions:

  • Incremental hemodialysis is a feasible option for selected pediatric patients.
  • This approach may enhance quality of life and decrease dialysis burden.
  • Clinical outcomes are not compromised when initiating incremental hemodialysis in children.
Abstract

Keywords:
HemodialysisIncremental dialysisPediatricsTwice-a week

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