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Infiltrative basal cell carcinoma: a nonsclerosing subtype.
The Journal of Dermatologic Surgery and Oncology
|August 1, 1986
Summary
Infiltrative basal cell carcinoma (BCC) is a unique subtype that is more destructive and harder to treat than nodular BCC. Diagnosis criteria are presented for this nonsclerotic skin cancer.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Basal cell carcinoma (BCC) is the most common type of skin cancer.
- Infiltrative BCC is a recognized histologic subtype with distinct clinical behavior.
- Understanding subtype differences is crucial for effective treatment planning.
Purpose of the Study:
- To present diagnostic criteria for infiltrative basal cell carcinoma.
- To emphasize the nonsclerotic nature of this BCC subtype.
- To compare the destructiveness and treatment difficulty of infiltrative BCC versus nodular BCC.
Main Methods:
- Histologic review of 174 consecutive BCC cases.
- Referral for Mohs micrographic surgery.
- Comparative analysis of infiltrative (29 tumors) and nodular BCC subtypes.
Main Results:
- Established diagnostic criteria for infiltrative BCC.
- Highlighted its nonsclerotic characteristics.
- Demonstrated infiltrative BCC to be significantly more destructive and challenging to treat than nodular BCC.
Conclusions:
- Infiltrative BCC requires specific diagnostic consideration.
- Its nonsclerotic nature may contribute to its aggressive behavior.
- Treatment strategies for infiltrative BCC should account for its increased destructiveness and difficulty.