Related Experiment Video
Updated: Jul 26, 2025

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia
Published on: November 15, 2024
Hyperglycemic Hemichorea: A Case Report
Joana Lopes1, Eulália Antunes1, Bárbara Oliveira1
1Internal Medicine, Hospital de Braga, Braga, PRT.
Non-ketotic hyperglycemic hemichorea-hemiballismus is a rare movement disorder linked to uncontrolled diabetes. Prompt diagnosis and metabolic control, including insulin therapy, can effectively resolve these involuntary movements.
Area of Science:
- Neurology
- Endocrinology
- Radiology
Background:
- Chorea and ballism are hyperkinetic movement disorders with diverse etiologies.
- Non-ketotic hyperglycemic hemichorea-hemiballismus (NHH) is a rare complication of poorly controlled diabetes mellitus.
- NHH presents with characteristic MRI findings in the basal ganglia.
Observation:
- A 74-year-old woman with type 2 diabetes presented with acute, involuntary movements of her left side.
- Her blood glucose was severely elevated (541 mg/dL) without ketosis, and HbA1c was 14%.
- Brain MRI revealed T1 hyperintensity in the right corpus striatum, consistent with NHH.
Findings:
- The patient's involuntary movements resolved after insulin therapy and haloperidol administration.
- Metabolic optimization was key to the successful treatment of the choreiform movements.
- The case highlights the diagnostic utility of neuroimaging in conjunction with clinical presentation.
Implications:
- Early recognition of NHH is crucial for timely intervention and management.
- Decompensated diabetes can manifest as a neurological emergency, necessitating prompt metabolic control.
- Raising awareness for NHH can improve diagnosis and patient outcomes in diabetic populations.
More Related Videos
Related Concept Videos
Hypoglycemia and Glucagon
SBAR II: Application of SBAR
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
Diabetes: Symptoms, Diagnosis, and Complications
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Acute Pancreatitis II: Clinical Manifestations and Management

