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Synthesis of Near-Infrared Emitting Gold Nanoclusters for Biological Applications
Published on: March 22, 2020
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Isomer-Selective Conversion of Au Clusters by Au(I) Thiolate Insertion
Yuki Chiga1, Ryo Takahata1,2, Wataru Suzuki2
1Graduate School of Science, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan.
Inorganic Chemistry
|June 21, 2023
Summary
This study achieves isomer-selective conversion of gold clusters using gold(I) thiolate complexes. This method precisely controls the structure of larger gold clusters, advancing rational cluster design.
Area of Science:
- Nanomaterials Chemistry
- Surface Science
- Cluster Chemistry
Background:
- Controlling the specific isomeric structure of gold clusters is crucial for their application.
- Existing methods for gold cluster conversion often yield mixtures of isomers, limiting rational design.
Purpose of the Study:
- To demonstrate isomer-selective conversion of gold clusters using gold(I) thiolate complexes.
- To investigate the mechanism of cluster growth and structural preservation during conversion.
Main Methods:
- Electrospray ionization mass spectrometry (ESI-MS) to analyze cluster intermediates and products.
- UV-visible (UV-vis) spectroscopy to characterize the electronic properties and isomeric composition of the gold clusters.
Main Results:
- High-yield, isomer-selective conversion of Au18(cyclohexanethiolate)14 to Au24(SR)x(cyclohexanethiolate)y was achieved using gold(I) thiolate (AuSR) complexes.
- ESI-MS revealed stepwise insertion of AuSR units, maintaining an even number of added units and preserving the core electron count.
- UV-vis analysis confirmed the selective formation of a single Au24 isomer, unlike the non-selective reaction with free thiols.
Conclusions:
- Gold(I) thiolate complexes enable precise control over gold cluster growth, leading to isomer-selective synthesis.
- The core structure of the initial gold cluster is preserved during the conversion process.
- This approach offers a pathway for the rational design of specific gold cluster architectures.
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