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Outcomes of Heart Failure Hospitalizations in Adult Patients With Coarctation of Aorta: Report From National
Amith Seri1, Nischit Baral1, Amman Yousaf1
1Department of Internal Medicine, McLaren Health Care and Michigan State University, Flint, MI.
Insights
Coarctation of aorta (CoA) patients admitted for heart failure are younger and require more resources. However, CoA does not significantly increase in-hospital mortality for heart failure admissions.
Area of Science:
- Cardiology
- Congenital Heart Disease
- Heart Failure Research
Background:
- Coarctation of the aorta (CoA) is a prevalent congenital heart defect.
- CoA is associated with an increased risk of early diastolic and systolic heart failure.
- Understanding the impact of CoA on heart failure hospitalizations is crucial for resource allocation and patient management.
Purpose of the Study:
- To evaluate the impact of coarctation of the aorta (CoA) on heart failure hospitalization outcomes.
- To compare healthcare resource utilization and mortality in heart failure patients with and without CoA.
Main Methods:
- Retrospective cohort study utilizing the National Inpatient Sample (NIS).
- Comparison of heart failure hospitalization outcomes between patients with and without CoA.
- Analysis of patient demographics, length of stay, incidence of cardiogenic shock, and in-hospital mortality.
Main Results:
- An increasing prevalence of CoA-related heart failure admissions was observed over the past decade.
- Heart failure patients with CoA were significantly younger (mean age 57 vs. 71.6 years) and had a longer length of stay (7.4 vs. 5.4 days).
- Patients with CoA exhibited a higher incidence of cardiogenic shock (6.5% vs. 2.1%), but in-hospital mortality did not differ significantly (OR 1.45).
Conclusions:
- Coarctation of the aorta increases healthcare resource utilization in patients hospitalized for heart failure.
- CoA does not appear to significantly elevate in-hospital mortality for heart failure admissions.
- These findings highlight the substantial burden of CoA on healthcare systems within the context of heart failure management.
Abstract:
Coarctation of aorta (CoA) is a common congenital anomaly which portends patients to early diastolic and systolic heart failure. In this retrospective cohort study, we aimed to evaluate the impact of CoA on heart failure hospitalization. Using the national inpatient sample, the study compared the outcomes of heart failure hospitalization between patients with and without CoA. We noted increasing prevalence of CoA related heart failure admissions over the last decade. Heart failure patients with CoA were younger (mean age 57 vs 71.6 years, P < 0.001), had a longer length of stay (7.4 vs 5.4 days, P < 0.001), and a higher incidence of cardiogenic shock (6.5% vs 2.1%, P = 0.001). However, there was no statistically significant difference in in-hospital mortality (OR 1.45, 95% CI: 0.58, 3.62, P = 0.421) between both groups. These findings demonstrate that CoA increase healthcare resource utilization in patients admitted with heart failure without any significant increase in in-hospital mortality.
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