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Updated: Jul 26, 2025

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
Left Atrial Appendage Closure with the Watchman FLX System in a Patient with Hypertrophic Cardiomyopathy on Dialysis
Takashi Funaki1, Mike Saji1,2, Mai Terada1
1Department of Cardiology, Sakakibara Heart Institute, Japan.
Insights
Hypertrophic cardiomyopathy patients with atrial fibrillation usually get anticoagulation. However, left atrial appendage closure using the Watchman FLX system may be a safe alternative for those requiring hemodialysis.
Area of Science:
- Cardiology
- Interventional Cardiology
Background:
- Hypertrophic cardiomyopathy (HCM) frequently co-occurs with atrial fibrillation, a condition typically managed with anticoagulation.
- Anticoagulation is contraindicated in patients requiring hemodialysis (HD) due to elevated bleeding risks.
Observation:
- A case report details a patient with dilated phase HCM and persistent atrial fibrillation who also required hemodialysis.
- This patient underwent left atrial appendage closure (LAAC) using the Watchman FLX system.
Findings:
- Left atrial appendage closure (LAAC) with the Watchman FLX system was successfully performed.
- This procedure offers a potential alternative to systemic anticoagulation in this high-risk patient cohort.
Implications:
- Left atrial appendage closure (LAAC) may provide a viable stroke risk reduction strategy for patients with hypertrophic cardiomyopathy and atrial fibrillation who are on hemodialysis.
- This case highlights the potential of device-based closure as an alternative to antithrombotic therapy in specific complex patient profiles.
Abstract:
Patients with hypertrophic cardiomyopathy (HCM) often have atrial fibrillation, and empiric anticoagulation is recommended in these patients, regardless of other risk factors. However, anticoagulation is not recommended for patients who require hemodialysis (HD) because of the high bleeding risk. We herein report a case of left atrial appendage closure (LAAC) using the Watchman FLX system for a dilated phase HCM patient complicated by persistent atrial fibrillation and requiring HD. LAAC with the Watchman FLX system may be an alternative to antithrombotic medications in patients with dilated HCM complicated by atrial fibrillation and requiring HD.
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