A Paradigm Shift in Primary Liver Cancer Therapy Utilizing Genomics, Molecular Biomarkers, and Artificial...

Area of Science:

• Oncology
• Genomics
• Biotechnology

Background:

• Primary liver cancer is a major global health concern, ranking sixth in incidence and third in mortality.
• Conventional treatments have limited efficacy, underscoring the need for novel therapeutic strategies.

Purpose of the Study:

• To review recent breakthroughs in primary liver cancer therapies.
• To explore the role of genomics, molecular biomarkers, and artificial intelligence in advancing treatment.
• To discuss future directions in immunotherapy and locoregional therapies.

Main Methods:

• Literature review of current research in primary liver cancer.
• Analysis of emerging trends in cancer genomics and biomarker discovery.
• Examination of artificial intelligence applications in oncology.

Main Results:

• Genomic and molecular profiling are revealing new therapeutic targets.
• Artificial intelligence shows promise in improving diagnosis and treatment selection.
• Immunotherapy and advanced locoregional therapies are evolving rapidly.

Conclusions:

• Integrating genomics, biomarkers, and AI is crucial for personalized primary liver cancer treatment.
• Further research into immunotherapy and refined locoregional approaches holds significant potential.
• Addressing the complexity of liver cancer requires a multidisciplinary and innovative therapeutic strategy.