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Updated: Jul 26, 2025

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
Published on: January 9, 2019
Mononeuropathy multiplex as an uncommon presentation of intravascular lymphoma: A case report
Bahram Haqi-Ashtiani1, Parichehr Moghaddam1, Farzaneh Barzkar2
1Firoozgar Hospital, School of Medicine Iran University of Medical Sciences Tehran Iran.
Key Clinical Message:
Although intravascular lymphoma rarely presents with peripheral neuropathy, learning about this presentation can lead to timely diagnosis and improved prognosis in patients with intravascular lymphoma.
Abstract:
A 64-year-old man presented with asymmetric paresthesia and subsequent weakness of his feet and a 10 kg weight loss over 40 days. Electrodiagnostic studies revealed distal axonal sensory-motor polyneuropathy with ongoing axonal loss. A peroneal nerve biopsy showed intravascular proliferation of CD-20 positive lymphocytes, which suggested intravascular large B-cell lymphoma.
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