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Erectile dysfunction, depression, and anxiety in patients with functional anorectal pain: a case-control study
Huang Fu Ma1, Ying Ying Zhang2, Qiang Yu1
1Proctology Department, China-Japan Friendship Hospital, Beijing 100029, People's Republic of China.
The Journal of Sexual Medicine
|June 23, 2023
Summary
Men with functional anorectal pain (FARP) experience higher rates of erectile dysfunction (ED), depression, and anxiety. Pain severity significantly impacts these conditions, highlighting the need for lifestyle adjustments and comprehensive treatment.
Area of Science:
- Urology
- Gastroenterology
- Psychiatry
Background:
- Functional anorectal pain (FARP) is associated with erectile dysfunction (ED) and psychological distress in men.
- Investigating risk factors for FARP and its impact on ED, depression, and anxiety is crucial for understanding patient well-being.
Purpose of the Study:
- To identify risk factors for FARP in male outpatients.
- To assess the impact of FARP on erectile function, depression, and anxiety.
Main Methods:
- A case-control study involving 406 male participants (323 FARP, 73 controls).
- Utilized validated questionnaires for assessing erectile function, depression, and anxiety.
- Employed logistic regression analyses to determine influencing factors and associations.
Main Results:
- FARP patients exhibited significantly higher rates of ED (59.8%), depression (20.7%), and anxiety (31.5%) compared to controls.
- FARP was independently associated with increased risk for ED (2.47x), depression (2.73x), and anxiety (2.67x).
- Increased pain severity correlated with higher incidence of ED, depression, and anxiety.
Conclusions:
- FARP is significantly correlated with ED, depression, and anxiety, with pain severity exacerbating these conditions.
- Lifestyle factors like alcohol intake, work pressure, and prolonged sitting are linked to FARP severity.
- Comprehensive, interdisciplinary treatment addressing both physical and psychological aspects is recommended for patients with FARP.
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