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Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases
Ademola S Ojo1, Adedoyin Shittu1, Stacy Amadife1
1Department of Internal Medicine, Howard University Hospital, Washington, DC, USA.
Abstract:
The expression of hormone receptors (estrogen and progesterone) and human epidermal growth factor receptor-2 (HER2) has been used for both therapeutic and prognostic purposes in the management of breast cancer. The presence of a discordant receptor status complicates the approach to treatment in patients with synchronous bilateral breast cancer. We describe the case of a 45-year-old female with synchronous bilateral breast cancer with a triple-negative tumor and a contralateral HER2-positive tumor and discussed the impact of this on the approach to therapeutic management.

