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Updated: Jul 25, 2025

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes
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A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes

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Improved extracellular vesicle-based mRNA delivery for familial hypercholesterolemia treatment

Zheng Yang1,2,3, Panpan Ji4, Zhelong Li5

  • 1College of Otolaryngology, Head and Neck Surgery, Chinese PLA General Hospital, Beijing 100853, China.

Theranostics
|June 23, 2023
PubMed

Keywords:
Extracellular vesiclesRNA aptamerendosome escapeloading efficiencylow-density lipoprotein receptortherapeutic mRNA

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