Related Experiment Video
Updated: Jul 25, 2025
Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research
Published on: December 15, 2023
Branch-site occlusion sign predicts the embolic origin of acute ischemic stroke: a meta-analysis
Xinzhao Jiang1, Zongjie Shi1, Peng Wang1
1Center for Rehabilitation Medicine, Department of Neurology, Zhejiang Provincial Peoples Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China.
Objective:
The study aimed to investigate whether branch-site occlusion (BSO) sign could predict the etiology of acute intracranial large artery occlusion (ILVO) and the stentriever (SR) response.
Methods:
We systematically reviewed studies that evaluated the predictive role of BSO for the etiology of ILVO-AIS or EVT outcome between 1 January 2000 and 31 August 2022 from PubMed, Embase, and Web of Science.
Results:
The sensitivity and specificity of BSO sign predicting etiology of ILVO-AIS were 0.87 (95% CI 0.81-0.91) and 0.64 (95% CI 0.33-0.87), respectively. The sensitivity and specificity of BSO sign predicting stentriever response were 0.84 (95% CI 0.63-0.94) and 0.61 (95% CI 0.18-0.92), respectively.
Conclusion:
The BSO sign could be a valid and precise imaging marker to predict embolism caused ILVO-AIS and recanalization success by SR without rescue therapy.
