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Updated: Jul 25, 2025
08:34
Isolation of Atrial Myocytes from Adult Mice
Published on: July 25, 2019
10.5K
[Cardiac arrhythmias and amyloidosis]
Jorge Salinas-Arce1, Raúl Alca-Clares1,2, Ana Cecilia Gonzales-Luna1,3
1Unidad de Arritmias, Clínica Delgado. Lima, Perú. Unidad de Arritmias Clínica Delgado Lima Perú.
Summary
Cardiac amyloidosis (CA) causes heart rhythm issues, including atrial fibrillation and conduction system disease, often before diagnosis. Management strategies are crucial for patient outcomes.
Area of Science:
- Cardiology
- Electrophysiology
- Amyloidosis Research
Context:
- Cardiac amyloidosis (CA) is a infiltrative cardiomyopathy.
- CA involves extracellular myocardial deposition of amyloid fibrils.
- This leads to heart failure, arrhythmias, and conduction abnormalities.
Purpose:
- To review current guidelines for managing arrhythmias in CA.
- To summarize data on arrhythmias in CA.
- To describe evidence-based strategies for managing CA-related arrhythmias.
Summary:
- Cardiac amyloidosis frequently causes arrhythmias like atrial fibrillation and AV node disease.
- Arrhythmias can occur early in CA, even before diagnosis.
- Implantable cardioverter-defibrillators have not improved survival for ventricular arrhythmias in CA.
Impact:
- Provides a comprehensive overview of arrhythmias in cardiac amyloidosis.
- Clarifies guideline recommendations for arrhythmia management in CA.
- Offers evidence-based strategies for clinical practice.
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