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Hematocrit and anxiety.

R J Mathew, W H Wilson

    Journal of Psychosomatic Research
    |January 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    This study found that while stress and anxiety increase, hematocrit levels do not change. Epinephrine infusion elevated anxiety and blood pressure but did not affect hematocrit or plasma volume.

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    Area of Science:

    • Psychiatry
    • Hematology
    • Cardiology

    Background:

    • Stress is commonly thought to elevate hematocrit.
    • Generalized anxiety disorder (GAD) is a condition characterized by significant anxiety.
    • Hematocrit, a measure of red blood cell volume, is a potential indicator of physiological stress.

    Purpose of the Study:

    • To investigate the relationship between anxiety levels and hematocrit.
    • To determine if epinephrine administration affects hematocrit in anxious patients.

    Main Methods:

    • Compared hematocrit and psychological measures (state anxiety, trait anxiety, depression) in GAD patients and healthy controls.
    • Administered intravenous epinephrine or saline to anxious patients and re-measured physiological and psychological parameters.

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    Main Results:

    • No significant differences in hematocrit were found between GAD patients and controls.
    • GAD patients exhibited higher state anxiety, trait anxiety, and depression scores.
    • Epinephrine infusion increased state anxiety, pulse rate, and systolic blood pressure, but did not alter hematocrit or plasma volume.

    Conclusions:

    • Hematocrit levels do not appear to be directly influenced by generalized anxiety or acute stress induced by epinephrine.
    • Psychological stress markers are elevated in GAD, but this does not correlate with changes in hematocrit.