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Updated: Jul 25, 2025

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:15

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

138

Weight loss during follow-up in patients with acute heart failure: From the KCHF registry

Yuta Seko1, Takao Kato1, Takeshi Morimoto2

  • 1Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Plos One
|June 23, 2023
PubMed

Insights

Significant weight loss after acute heart failure discharge is linked to increased mortality. Monitoring weight changes post-discharge is crucial for predicting outcomes in heart failure patients.

Area of Science:

  • Cardiology
  • Heart Failure Research
  • Clinical Outcomes

Background:

  • Prognostic implications of post-discharge weight loss in acute heart failure (AHF) are not well-defined.
  • Understanding weight dynamics is key for managing AHF patients.

Purpose of the Study:

  • To investigate the association between weight loss from discharge to 6-month follow-up and clinical outcomes in AHF patients.

Main Methods:

  • Analysis of 686 AHF patients from the Kyoto Congestive Heart Failure registry.
  • Patients categorized into weight loss (≥5% decrease) and no weight loss groups at 6 months.
  • Longitudinal follow-up to assess clinical outcomes.

Main Results:

  • 13.1% of patients experienced ≥5% weight loss by 6 months.
  • Weight loss group showed distinct clinical characteristics including lower blood pressure and higher natriuretic peptide levels.
  • The 6-month cumulative incidence of all-cause death was significantly higher in the weight loss group (14.2% vs. 4.3%).

Conclusions:

  • A body weight loss of ≥5% at 6 months post-discharge is associated with increased risk of all-cause death in AHF patients.
  • This finding highlights the prognostic significance of post-discharge weight changes.
Abstract

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