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Advances in biomaterial-based cardiac organoids
Caixia Fan1, Jiaxiong He1, Sijia Xu1
1School of Life and Environmental Sciences, Shaoxing University, Shaoxing 312000, Zhejiang, China.
Biomaterials Advances
|June 23, 2023
Summary
Cardiac organoids offer a promising solution for heart failure, addressing limitations in drug therapy and transplantation. This review explores biomaterials and strategies for cardiac repair and regeneration using organoid technology.
Area of Science:
- Biotechnology
- Regenerative Medicine
- Cardiovascular Research
Background:
- Cardiovascular disease (CVD) is a leading cause of death globally, with heart failure incidence rising due to aging populations.
- Current treatments like drug therapy and heart transplantation face limitations, including limited myocardial regeneration, donor shortages, and high costs of alternatives.
- The significant treatment deficit for heart failure patients highlights the urgent need for innovative therapeutic strategies.
Conclusions:
- Cardiac organoids represent a significant advancement in addressing the limitations of current heart failure treatments.
- Further research and development in biomaterials and organoid technology are essential for clinical translation.
- Biomaterial-based cardiac repair holds promise for future cardiac regeneration strategies and improved patient outcomes.
