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Related Concept Videos

Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

1.7K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.7K
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

20
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
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Heart Failure I: Introduction01:27

Heart Failure I: Introduction

24
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
24
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

16
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
16
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

25
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
25
Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

111
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
111

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Related Experiment Video

Updated: Jul 25, 2025

A Surgical Model of Heart Failure with Preserved Ejection Fraction in Tibetan Minipigs
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A Surgical Model of Heart Failure with Preserved Ejection Fraction in Tibetan Minipigs

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Regional variations in heart failure: a global perspective.

Vidhushei Yogeswaran1, Danelle Hidano1, Andrea E Diaz2

  • 1Division of Cardiology, University of Washington, Seattle, Washington, USA.

Heart (British Cardiac Society)
|June 23, 2023
PubMed
Summary

Heart failure (HF) care shows significant global disparities. Understanding these variations in risk factors, treatment, and outcomes is crucial for improving cardiovascular health worldwide.

Keywords:
Global HealthHealth Care Economics and OrganizationsHeart Failure

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Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
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Area of Science:

  • Cardiology
  • Global Health
  • Health Disparities

Background:

  • Heart failure (HF) is a major global health issue with millions affected worldwide.
  • Despite therapeutic advances, significant disparities persist in HF risk factors, treatment, and outcomes across diverse populations and regions.
  • Underrepresentation of Asia, Africa, and South America in HF research limits understanding of global variations.

Purpose of the Study:

  • To provide an overview of global and regional variations in heart failure care and outcomes.
  • To highlight the critical need to understand factors contributing to disparities in HF care.
  • To inform interventions aimed at improving global cardiovascular health and mitigating the economic burden of HF.

Main Methods:

  • This narrative review synthesizes current research on global heart failure epidemiology and care.
  • It examines data from recent efforts and registries providing insights into HF patterns worldwide.
  • The review focuses on identifying and analyzing disparities in HF prevalence, risk factors, treatment, and outcomes across different regions.

Main Results:

  • Prevalence of HF and associated risk factors vary significantly by country and region.
  • There are substantial gaps in data regarding regional variations in HF treatment patterns and long-term outcomes.
  • Low- and middle-income countries, particularly in Asia, Africa, and South America, are underrepresented in HF studies.

Conclusions:

  • Addressing global and regional disparities in heart failure care is essential for improving cardiovascular health.
  • Further research and data collection, especially from underrepresented regions, are needed to fully understand HF variations.
  • Mitigating the social and economic costs of heart failure requires targeted interventions informed by a comprehensive understanding of global care patterns.